Grim-19 deficiency promotes decidual macrophage autophagy in recurrent spontaneous abortion
Dysregulation of decidual macrophages leads to the occurrence of recurrent spontaneous abortion (RSA).However, the role of macrophages in RSA occurrence remains unclear.In this study, we found that the expression of Grim-19 was decreased, and the expression of autophagy related proteins Beclin1, LC3B II/I and BNIP3 was markedly upregulated in decid